Quiste hidático esplénico, una rara topografía de una rara enfermedad / Splenic hydatid cyst, a rare topography of a rare disease / Cisto hidatico esplénico, uma topografia rara de uma doença rara

Primary splenic hydatid cyst is a rare entity even in endemic areas. In most cases it presents asymptomatically being diagnosed by imaging findings. Treatment is multimodal and individualized, being surgical treatment the one that allows an integral solution of the disease. Conventional surgery continues to be the "Gold standard" in its approach. We present the case of a patient with this condition and the resolution approached by the surgical team.

O cisto hidatides esplénico primário é uma entidade rara mesmo em áreas endémicas. Na maioria dos casos apresenta-se de forma assintomática, sendo diagnosticada através de resultados de imagem. O tratamento é multimodal e individualizado, com um tratamento cirúrgico que proporciona uma solução abrangente para a condição. A cirurgia convencional continua a ser a abordagem "padrão de ouro". Apresentamos o caso de um paciente com esta condição e a resolução abordada pela equipa cirúrgica.

El quiste hidático primario esplénico es una entidad poco frecuente aún en áreas endémicas. Se presenta en la mayoría de los casos de forma asintomática, siendo diagnosticado por hallazgo imagenológico. El tratamiento es multimodal e individualizado, siendo el tratamiento quirúrgico el que permite una solución integral de la dolencia. La cirugía convencional sigue siendo el "Gold estándar" en su abordaje. Presentamos el caso de una paciente con esta afección y la resolución abordada por el equipo de cirugía.

Manejo quirúrgico de la hidatidosis hepática en esta última década: ¿qué hemos aprendido? / Surgical management of liver hydatidosis in the last decade: what have we learned?

Resumen El manejo clínico de la hidatidosis hepática es complejo y se basa fundamentalmente en tres pilares: quirúrgico, percutáneo y farmacológico; los cuales en ocasiones pueden ser complementarios. La terapia debe definirse en función de las características, ubicación y tipo de quiste; a lo cual debe sumarse la experiencia del equipo médico, recursos disponibles y la adherencia de los pacientes al monitoreo a largo plazo. La cirugía es el tratamiento más utilizado, las técnicas percutáneas posiblemente puedan reemplazar a la cirugía en casos específicos. Sin embargo, a pesar de los avances en las técnicas quirúrgicas, en el uso de la quimioterapia y otros tratamientos, el manejo de hidatidosis hepática sigue siendo un problema importante, debido principalmente a la falta de consenso sobre qué procedimiento a utilizar es mejor. El objetivo de esta presentación es dar a conocer el amplio abanico de terapias existentes en el actual manejo de la hidatidosis hepática, así como indicar algunas sugerencias en la utilización de cada una de ellas.

The clinical management of hepatic hydatidosis is complex and is fundamentally based on three pillars: surgical, percutaneous and pharmacological; which can sometimes be complementary. Therapy should be defined based on the characteristics, location and type of cyst; to which must be added the experience of the medical team, available resources and the adherence of patients to long-term monitoring. Surgery is the most used treatment, percutaneous techniques can possibly replace surgery in specific cases. However, despite advances in surgical techniques, in the use of chemotherapy and other treatments, the management of liver hydatidosis continues to be a major problem; mainly due to the lack of consensus on which procedure to use is better. The objective of this presentation is to present the wide range of existing therapies in the current management of hepatic hydatidosis and some suggestions in the use of each one of them.

Quistectomía laparoscópica en quiste hidatídico hepático / Laparoscopic cystectomy in hidatidid cyst

Resumen Objetivo: Describir resultados en términos de morbilidad y mortalidad del tratamiento de quistes hidatídicos hepáticos (QHH) por vía laparoscópica en una serie de pacientes consecutivos. Comparar calidad de vida (CV) de pacientes sometidos a quistectomía laparoscópica (QL) con pacientes llevados a colecistectomía laparoscópica. Materiales y Método: Serie de casos con seguimiento de pacientes con QHH, sometidos a QL. Analizamos datos con Stata® 10.0, mediante medidas de tendencia central y dispersión. Describimos 4 variables, realizando seguimiento con tomografía computada (TC) abdominal. Aplicamos encuesta de calidad de vida SF-36. Resultados: Incluimos 12 pacientes, 58,3% de género femenino. Número de quistes 2,02 ± 1,56, volumen quístico mayor 809,16 ± 766,05 ml, diámetro de quiste mayor 11,77 ± 4,33 cm, predominando en lóbulo hepático derecho (58%). Tiempo operatorio promedio 234,1 ± 52,9 minutos. Estadía hospitalaria promedio 11,5 ± 14,5 días. Morbilidad en 16,6%, sin mortalidad posoperatoria. Seguimiento con imágenes promedio fue 7,9 ± 4,3 meses, encontrando cavidades residuales pequeñas y asintomáticas en 50% de pacientes. No reportamos recidivas. Al comparar CV con grupo de colecistectomía sólo encontramos diferencia respecto a vitalidad (p = 0,04). Discusión: Aunque nuestra serie es pequeña y presenta mayor tiempo quirúrgico (por selección de pacientes) y mayor estancia hospitalaria que en otras series de QL, presenta menor porcentaje de recidivas, de fístulas biliares y no presenta mortalidad, concordando con otras series de QL que la recomiendan como opción terapéutica. Conclusiones: La QL para el tratamiento de los QHH resulta una cirugía aceptable, con morbilidad y mortalidad comparable con reportes de cirugía abierta.

Aim: To describe results in morbidity and mortality terms of the hepatic hydatidosis (HHC) treatment by laparoscopic route in selected patients. In addition, compare the quality of life (QL) of cystomectized vs cholecystectomized patients, both laparoscopically. Materials and Method: Case series with follow-up of patients with HHC, undergoing laparoscopic cystectomy (LC). Data analysis, through measures of central tendency and dispersion, performed with Stata® 10.0. Analyzing 4 variables followed-up with abdominal computed tomography. A quality of life survey SF-36" was applied. Results: 12 patients were included, 58.3% female gender. Cysts number 2.02 ± 1.56, largest cystic volume 809.16 ± 766.05 ml, larger cyst diameter 11,77 ± 4,33 cm. Right hepatic lobe is predominantly 58%. Surgical time, 234.16 ± 52.95 minutes. Hospital stay, 11.58 ± 14.55 days. Morbidity 16.6%, with no postoperative mortality. Follow-up, performed at 7.9 ± 4.3 months, finding residual cavity in 50%, no recurrences were reported. At comparing QL with cholecystectomy group, we only found differences at the vitality item (p = 0,04). Discussion: Although our series is small and has a longer surgical time (by patient selection) and a longer hospital stay than in other LC series, it has a lower recurrences percentage, biliary fistulas, and no mortality, agreeing with other LC series that recommend it as a therapeutic option. Conclusions: The laparoscopic approach for the HHC treatment, is an acceptable surgery, with morbidity and mortality comparable to the reports of laparotomy surgery.

Application of a single-chain fragment variable (scFv) antibody for the confirmatory diagnosis of hydatid disease in non-endemic areas

Background: Hydatid disease is a serious parasitic disease threatening public health. Because of its rarity in non-endemic coastal areas, determining the nature and origin of a chronic, enlarged liver cystic mass is challenging in these regions. Under these circumstances, physicians need a confirmatory diagnostic tool beyond immunological and radiological examinations. This study investigated a novel human single-chain fragment variable (scFv) antibody for the confirmative diagnosis of 18 atypical hydatid disease cases in non-endemic coastal areas. Results: A scFv antibody against cystic echinococcosis was produced by genetic engineering and then applied to the immunohistochemical diagnosis of 18 cases of cystic echinococcosis presented in non-endemic coastal areas. The diagnosis of these cases by ultrasound and serum-based examinations was inconclusive. The 750 bp scFv antibody gene was expressed in COS-7 cells, and the antibody localized in the cytoplasm. The scFv antibody can detect the germinal layer and protoscolices of actively growing cysts but not of the degenerating protoscolices and has a diagnostic efficiency higher than that of single serum or ultrasound testing (P b 0.05). The combined use of scFv antibodies with serology and ultrasound diagnostics results in a diagnostic efficiency comparable to that of surgery. The scFv antibody can be used as a confirmatory test for the diagnosis of hydatid disease in non-endemic areas, providing a beneficial supplementary diagnostic method that complements traditional immune testing and ultrasonic radiology and thus helping physicians to effectively differentiate hydatid disease.

Effectiveness of the Live Births Information System in the Far-Western Brazilian Amazon / Eficácia do Sistema de Informação de Nascidos Vivos na Amazônia Extremo-Ocidental Brasileira

The Live Birth Information System (SINASC) was implemented in 1990 for the purpose of providing information about the live-birth characteristics for the establishment of specific health indicators. This work evaluates the information quality of SINASC in relation to its data completeness and coverage for five municipalities from the State of Acre from 2005 to 2010. Lack of information (not filled out or stated as "unknown") was estimated for each variable. Coverage was estimated comparing the Civil Register office statistics in accordance with the mother's municipality of residence. An increase in incompleteness of the majority of variables was observed, and also a decrease in coverage between 2005 and 2010 in these municipalities. These findings do not tally with results from the majority of studies that use SINASC as a data source. The results of this work highlight the relevance of continuous capacity building and the incentive for accurate and complete data inclusion, as well as awareness of the importance of SINASC for public health policies.

O Sistema de Informação de Nascidos Vivos (SINASC) foi implantado no ano de 1990 com o objetivo de fornecer dados sobre as características de nascidos vivos para o estabelecimento de indicadores de saúde específicos. Objetivo: O presente trabalho avalia a qualidade da informação do SINASC quanto à incompletude dos seus dados e da cobertura para cinco municípios do estado do Acre nos anos de 2005 e 2010. Métodos: Foi calculada a incompletude (definida como dados em branco/ignorado) de cada variável, assim como a cobertura desse sistema através da comparação com as estatísticas do Registro Civil, segundo município de residência da mãe. Resultados: Observou-se um aumento da incompletude da maioria das variáveis e uma diminuição da cobertura de 2005 para 2010 no conjunto dos municípios avaliados, destoando dos resultados obtidos na maioria dos estudos que utilizam o SINASC como fonte de dados. Conclusões: Os resultados deste trabalho apontam para a importância da contínua capacitação e também para o incentivo ao preenchimento dos dados de forma correta e completa, bem como a conscientização da importância do SINASC para as políticas públicas de saúde.

Hepatic hydatid cyst

No abstract available.

Características clínicas, radiológicas y laboratoriales de pacientes con hidatidosis hepática en un hospital de referencia nacional, Lima 1997-2010 / Clinical, radiological and laboratory features of liver hydatidosis of patients from a hospital of national reference, Lima 1997-2010

Objetivo: Describir las características clínicas, laboratoriales y radiológicas de pacientes con quiste hidatídico hepático tratados en el servicio de cirugía general de un hospital de referencia nacional de Lima (Perú). Materiales y métodos: Se realizó un estudio de casos, el cual incluyó a todos los pacientes con diagnóstico de quiste hidatídico hepático hospitalizados entre 1997 y 2010. Se recogieron datos sociodemográficos (edad, sexo, procedencia y actividad habitual), datos clínicos, laboratoriales, radiográficos y referidos al tratamiento. Resultados: El síntoma más frecuente fue el dolor abdominal (93,9%), en tanto que el signo más frecuente fue el incremento del span hepático (68,7%). El 86,4% de los pacientes tenían una formula leucocitaria dentro de rangos normales, la eosinofilia estuvo presente solo en el 25,9% de los casos. El lóbulo hepático derecho fue el más afectado (80%) y en el 40,8% de los pacientes se encontró afección de un solo segmento. En el 75,4% de los pacientes los quistes eran únicos. La complicaciones más frecuentes fueron: la comunicación a la vía biliar (48,9%), los abscesos hidatídicos (32,6%), la colangitis (4%) y el quiste hidatídico roto más peritonitis (4%). Conclusión: La población más afectada fueron adultos jóvenes de entre 30 a 39 años. La población estudiada reside en su mayoría en el departamento de Lima, pero provienen de departamentos en donde la hidatidosis hepática ha sido descrita como endémica. A pesar de que esta población es en su mayoría urbana, las características epidemiológicas no varían en relación a la descrita en investigaciones previas.

Objective: To describe the clinical, laboratory and radiological features of patients with hepatic hydatid cyst treated at the department of general surgery of a national referral hospital in Lima (Peru). Materials and methods: A cross-sectional study was performed, all patients diagnosed with hepatic hydatid cyst hospitalized between 1997 and 2010 were included. Sociodemographic data (age, sex, origin and usual activity), clinical, laboratory, radiographic and data referrals to treatment were collected. Results: The most common symptom was abdominal pain (93.9%), while the most frequent sign was the increase in liver span (68.7%). 86.4% of patients had a leukocyte formulated within normal ranges, eosinophilia was only present in 25.9% of cases. The right hepatic lobe was the most affected (80%) and in 40.8% of patient’s condition one segment was found. In 75.4% of patients the cysts were unique. The most frequent complications were: communication to the bile duct (48.9%), hydatid abscesses (32.6%), cholangitis (4%), hydatid cyst and broken more peritonitis (4%). Conclusion: The population more affected was young adults aged 30 to 39 years. The population studied lives mostly in the department of Lima, but come from departments where hepatic hydatid disease has been described as endemic. Although this population is mostly urban, epidemiological characteristics do not vary in relation to that described in previous research.

Hemangioma hepático poliquístico simulando un quiste hidatídico: reporte de un caso y revisión del tema / Polycystic liver hemangioma mimicking a hydatid cyst: a case report and review of the topic

Cavernous hemangiomas are the most common benign mesenchymal hepatic tumor. Most have a typical appearance, but atypical forms have been reported that can make diagnosis difficult. Objective: To show a case of cystic hemangioma mimicking a hydatid cyst. Case: 60 year old woman with abdominal pain. Abdominal ultrasound: polycystic lesion with parietal calcifications, 6 cm in size, in the left hepatic lobe. Computed tomography of the abdomen shows the lesion as a simple cyst. During conversation the patient revealed she lives with 13 dogs. Hydatid disease was suspected and treatment with albendazole and segmental hepatectomy was indicated. A hemorrhagic tumor biopsy compatible with infarcted hemangioma was obtained. Discussion: The typical hepatic hemangioma is presented in ultrasound as an echogenic mass with posterior acoustic enhancement. The contrasted CT also presents with a classic pattern. Among the atypical presentations the cystic form is extremely rare and has only been mentioned in a few reports.

Hemangioma cavernoso es el tumor hepático mesenquimático benigno más frecuente. La mayoría tiene un aspecto típico, pero se han reportado formas atípicas que pueden dificultar el diagnóstico. Objetivo: Mostrar un caso de hemangioma quístico simulando a un quiste hidatídico. Caso: Mujer de 60 años consulta por dolor abdominal. Ecografía abdominal: lesión poliquística con calcificaciones parietales de 6 cm en el lóbulo hepático izquierdo. Tomografía computada de abdomen muestra la lesión como un quiste simple. Dirigidamente la paciente revela convivir con 13 perros. Se sospechó hidatidosis y se indicó albendazol y hepatectomía segmentaria. Se obtuvo un tumor hemorrágico con biopsia compatible con hemangioma infartado. Discusión: El hemangioma hepático típico se presenta ecográficamente como una masa ecogénica con refuerzo acústico posterior. La TC contrastada también presenta un patrón clásico. Dentro de las presentaciones atípicas la forma quística es extremadamente rara y sólo ha sido mencionada en escasos reportes.

Guía provincial para el manejo de la hidatidosis hepática: Neuquén, 2012 / Provincial guide for the management of hepatic hydatidosis: Neuquén, 2012

La hidatidosis es una parasitosis zoonótica, causada por el cestode Echinococcus (E.) granulosus. En nuestro país es un importante problema de salud pública al ser considerada como enfermedad endémica, especialmente en regiones como la provincia de Neuquén, donde uno de sus pilares económicos es la actividad ganadera, especialmente la cría de ovinos y caprinos.

Cystic echinococcosis: a disease mimicking cancer in a non-endemic country report of two cases / Equinococosis quística: una enfermedad con apariencia de cáncer en un país no endémico: reporte de eos easos

Echinococcosis is a parasitic disease that involves dogs as definitive host and sheep as intermediate host. Humans become infected incidentally through fecal-oral contact, particularly in the course of playful and close contact with an infected dog. Mexico is considered a region that is virtually free of cystic echinoccocosis. This manuscript describes two cases that were referred to a tertiary-care oncology hospital with a diagnosis of cancer. In one case, the presumptive diagnosis was liver cancer because abdominal ultrasonography revealed a low-density mass in the right hepatic lobe. Drainage was performed and cytologic examination of the fluid showed multiple Echinococcus cyst as well as prostoscolex. The case was resolved with percutaneous drainage and administration of albendazole for two months. In the second case, the patient was referred with a diagnosis of disseminated cervical cancer. A cyst was identified in the upper right lung lobe; a diagnostic puncture was performed showing an Echinococcus cyst. This resolved solely with two months of albendazole administration.

La equinococosis, conocida también como hidatidosis, es una enfermedad parasitaria que comprende a los perros como hospedador definitivo y a las ovejas como huésped intermedio. Los seres humanos se infectan casualmente por contacto feco-oral, particularmente al jugar y estar en estrecho contacto con un perro infectado. México es considerado una región que está prácticamente libre de equinococosis quística. Este trabajo describe dos casos que fueron referidos con un diagnóstico de cáncer a un hospital oncológico de atención terciaria. En un caso, el diagnóstico presuntivo fue cáncer del hígado, porque la ultrasonografía abdominal reveló una masa de baja densidad en el lóbulo hepático derecho. Se hizo un drenaje y el examen citológico del fluido mostró quistes múltiples de equinococos así como la presencia de protoescólex. El caso se resolvió con drenaje percutáneo y administración de albendazol durante dos meses. En el segundo caso, la paciente fue remitida con un diagnóstico de cáncer cervical diseminado. Se identificó un quiste en el lóbulo superior de pulmón derecho. La punción diagnóstica realizada reveló un quiste equinocócico, que se resolvió simplemente con dos meses de administración de albendazol.

Hepatic hydatid cyst: a non-surgical approach / Cisto hidático hepático: abordagem não cirúrgica

Echinococcosis/hydatidosis is common in societies where agriculture and livestock are frequent, and represents a public health problem. The therapeutic management depends on the cyst's characteristics, the patient, and surgical contraindications. Endoscopic retrograde cholangiopancreatography is a valuable tool in the diagnosis and treatment of complicated hepatic hydatid disease. Ultrasonography is a useful diagnostic, therapeutic and follow-up tool. The authors report a case of a 56 years old patient who was diagnosed with a hepatic hydatid cyst in the IVa/VIII segments, describe the therapeutic options and 50 months of disease-free follow-up.

A equinococose/hidatidose é comum em sociedades onde predominam a agricultura e a criação de gado, sendo um problema de saúde pública. As várias opções terapêuticas dependem das caraterísticas do quisto, do doente e da eventual presença de contraindicações cirúrgicas. A colangiopancreatografia retrógrada endoscópica constitui uma válida ferramenta no diagnóstico e tratamento da doença hidática hepática complicada. A ecografia é um instrumento útil no diagnóstico, na terapêutica e seguimento. Os autores apresentam um caso de uma doente de 56 anos a quem foi diagnosticado um quisto hidático hepático nos segmentos IVa/VIII, descrevem as opções terapêuticas e o seguimento de 50 meses livres de doença.

Quince años de experiencia clínica con hidatidosis / Clinical presentation of hydatid disease during 15 years: a case series from Santiago, Chile

Introduction: Hydatidosis is a neglected parasitic disease that is endemic in Chile. We present the clinical experience of a single center in Santiago from 1996 to 2010. Methods: Cases were identified using hospital's database. Clinical and pathological features, treatment and outcomes were retrospectively analyzed. Results: In total, 23 patients were identified requiring 30 surgical interventions. Median age was 40 years old (range 5 to 73), and 76.5% visited or resided in regions of known endemicity in Chile. Abdominal cysts were predominant (78.3%), and most patients were symptomatic (73.9%). Elimination of cyst material by cough was reported in 42.9% of patients with symptomatic thoracic cysts. Eosinophilia was present in 41.2% of patients, and 57.1% had positive serology for hydatidosis. Aill patients underwent surgical treatment, in 60.9% in combination with albendazole treatment. While the majority of liver cysts (88.9%) were treated by complete cyst resection, lung cysts (83.3%) were predominantly treated by cyst resection plus capitonnage. Pathological examination revealed fertile cysts in 24%. Postsurgical morbidity was frequent (37.9%), and 13.3% of the series required readmission for this cause. Near 25% of patients remained in hospital > 14 days, a feature associated with fever during admission (p < 0.05). No recurrence was reported in the fraction of patients that were followed-up for 2 years or more. Conclusions: Our analysis of 23 cases demonstrates that patients were mainly adults suffering from abdominal cysts. Most patients were successfully treated by surgery with or without antiparasitic drugs but complications leading to prolonged hospital stays and readmissions were not infrequent.

Introducción: La hidatidosis es una enfermedad endémica en Chile. Se presenta la experiencia clínica de un hospital en Santiago, desde 1996 al 2010. Métodos: Los casos fueron identificados usando las bases de datos institucionales y se analizaron las características clínicas y patológicas, el tratamiento y la evolución en forma retrospectiva. Resultados: Se identificaron 23 pacientes intervenidos en 30 oportunidades. La mediana de edad fue de 40 años (rango 5 a 73) y 76,5% visitó o residía en zonas endémicas en Chile. Los quistes abdominales fueron predominantes (78,3%) y la mayor parte de los pacientes eran sintomáticos (73,9%). Un 42,9% de aquellos con quistes sintomáticos torácicos reportó eliminación de vesículas con la tos. Un 41,2% presentó eosinofilia y 57,1% tuvo serología positiva para hidatidosis. Todos los pacientes fueron tratados quirúrgicamente, en 60,9% en combinación con albendazol. La mayoría de los quistes hepáticos fueron tratados con cirugía radical (88,9%) y los pulmonares predominantemente con quistostomía y capitonaje (83,3%). Un 24% de los quistes eran fértiles. La morbilidad post-quirúrgica fue frecuente (37,9%) y 13,3% de la serie requirió reingresos por esta causa. Cerca de 25% de los pacientes estuvo hospitalizado por más de 14 días, un fenómeno asociado con la presencia de fiebre por complicación séptica al ingreso (p < 0,05). No se registraron recurrencias en la fracción de pacientes seguidos por más de dos años. Conclusiones: La hidatidosis afecta principalmente a adultos en su cavidad abdominal. Aunque los pacientes fueron tratados exitosamente con cirugía, las complicaciones, estadías prolongadas y reingresos por esta causa no fueron infrecuentes.

Hidatidosis poliquística autóctona en dos pacientes Yanomami en el Alto Orinoco, Amazonas, Venezuela / Polycystic hydatid disease in two patients indigenous Yanomami in the Upper Orinoco, Amazonas, Venezuela

La infección por Echinococcus sp. es hipoendémica en Venezuela. Sólo cuatro casos de hidatidosis autóctona por E. vogeli han sido reportados, tres de ellos en la región de la Guayana venezolana. En Febrero del año 2009 se realizó el diagnóstico clínico-sero-epidemiológico de hidatidosis poliquística en una paciente femenina de la etnia Yanomami, procedente de Parima B, Alto Orinoco, en la Amazonía venezolana. Se resolvió con tratamiento médico y quirúrgico por laparoscopia y se evidenció en el quiste la presencia de ganchos rostelares compatibles con E. vogeli. En Abril del 2009 en una segunda paciente Yanomami de igual procedencia, se le diagnosticó hidatidosis por E. vogeli siendo operada exitosamente por cirugía laparoscópica asistida por robot. Dos casos humanos en una misma población y la presencia de factores de riesgo como la tenencia de perros domésticos y la comunicación por informantes indígenas del hallazgo de quistes en hígados de animales de cacería (Cuniculus paca o lapa y Dasyprocta sp. o picure), hacen pensar en transmisión activa en la cuenca del Alto Orinoco y en zonas selváticas de la Guayana venezolana. El presente, es el primer registro de casos de hidatidosis poliquística en indígenas de la etnia Yanomami.

Infection by Echinococcus sp. is hypoendemic in Venezuela. Only four cases of autochthonous E. vogeli hydatidosis have been reported, including three in the Venezuelan region of Guayana. In February 2009, based on epidemiological data, signs and symptoms and serological tests, a female patient of the Yanomami ethnic group, was diagnosed with a polycystic hydatid disease in Parima B, Alto Orinoco, in the Venezuelan Amazon. Rostellar hooks compatible with E. vogeli were found in the cyst. It was resolved with medical and surgical treatment by laparoscopy. A second Yanomami patient from the same location was diagnosed with E. vogeli hydatidosis in April 2009, being successfully operated with robot-assisted laparoscopy. Two human cases in the same population and the presence of risk factors such as domestic dog ownership and findings of cysts in livers of hunted animals (such as Cuniculus and Dasyprocta sp.) reported by indigenous informants, suggest active transmission in the Upper Orinoco basin and forested areas of the Venezuelan Guayana. These are the first reported cases of polycystic hydatid disease of the Yanomami ethnic group.

[Hydatid cust of the spigelian lobe of the liver: diagnosis and treatment]

Surgery of the hepatic of hygdated cysts is a current practical procedure in Marocco due to the endemic context it is generally simple, and the surgical technique is viell cadified. Nevertheless certain hepatic localization like segment I may engeder difficulties and operatory complications that the surgeon must know for a better management. This is a retrospective study over ten years, it concerns ten patients with hydatid cyst affecting the Spigelian lobe with or without other localization. There is a female predominance the mean age is 43 years. Four patients were already operated on for liver hydatid cyct: two had involvement of caudal lobe. The clinical symptoms were not specific. Diagnostic imaging is mainly based on ultrasound and CT. All the patients were operated by laparotomy. Five patients had an hydatid cyst in caudal lobe only, four other associated hepatic lesions, and one case had a peritoneal hydatid disease. Type I was found in 2cases, type III in 5, type IV in one case and infected cyst in 2 cases. At surgical exploration it was found that caudael lobe cyst was intimatel anterioly with the hilum and the hepatic pedicle and with the inferior vena cava retrohepatic posterioly and at the right sue. We performed resection of the prominent dome ; the residual cavity was treated with hydrogen peroxide and systematically drained. The immediate postoperative were simple, the postoperative hospital stay was between 8 and 18 days. The surgical treatment of segment I hepatic hydatid cyst obyes the principals of hydated surgery and involues an important large vascular or buliarg wound risk. The resection of the prominent dome is an intervention simple, rapid and hemorrhagic with low mortality, but fails to eluminate a residual cavity may be ne seat of callection. Conservative treatment remains the gold standard, provided that there is a good postoperative monitoring and adequate management of biliary complications or infection

Liver hydatid cyst: pattern and methods of surgical treatment

Hydatidosis of liver is very old surgical problem worldwide and one of the commonest parasitic diseases that affect the man's health. In humans, 50% to 75% of hydatid cysts occur in the liver. The radical surgical removal of the cystic lesion remains the mainstay of treatment with a high success rate. The aim of this paper to report the surgical management of liver hydatid diseases in Iraq. 34 patients [59% males, 41% females] were observed during the period from April 2008 to May 2010, the mean age is 42 years. All patients were examined clinically and diagnosis obtained radiologically [ultrasonography, CT scan and in selected cases MRI], operative and postoperative details were recorded for every patient. The mean age of the patients was 42 years [range, 16-62 years]. 20 patients [59%] were males and 14 patients [41%] were females. The peak age group affected was between 3[rd] - 6[th] decades in 70.5%. The disease was primary in 23 patients [68%] and recurrent in patients [32%]. The cyst was single in 14 patients [41%] and multiple in 20 patients [59%]. Fifty percent multiple hydatid disease was recurrent, while the other 50% was primary. The Rt. Lobe of the liver was affected in 19 cases [56%], the Lt. lobe was affected in 4 patients [12%], and both lobes were involved in 11 patients [32%]. The clinical presentation include: upper abdominal pain/ discomfort in 18 patients [53%], palpable mass in 5 patients [14.7%], jaundice in 3 patients [8%], acute abdomen in 2 patients [6%], incidental findings in 6 patients [17.5%]. Mode of surgical treatment was as follow: excision and external tube drainage in 14 patients [41%], excision and partial pericystectomy [resection of redundant cyst wall and the residual cavity left open] in 7 patients [20.5%], excision and omentoplasty in 6 patients [17.5%], excision and primary suturing of the cyst wall and filling the cavity with normal saline in 5 patients [15%], and excision and marsupialization in 2 patients [6%]. No significant statistical difference in terms of morbidity and mortality between different surgical procedures, however cystectomy with external drainage was considered the standard surgical procedures especially in large sized cysts and bile communicate done

Cistoadenoma biliar como diagnóstico diferencial de hidatidosis hepática: reporte de caso / Biliary cystadenoma as differential diagnosis of hepatic hydatidosis: case report

The biliary cystadenoma represents a rare cystic tumor that may compromise the liver and the extrahepatic bile duct. This tumor accounts for less than 5 percent of solitary non-parasitic cysts of the liver. Our aim is to report a clinical case as well as to discuss some issues concerning diagnosis and treatment options for this type of injuries.

El cistadenoma biliar es un tumor quístico infrecuente que puede comprometer el hígado y la vía biliar extrahepática. Este tumor representa menos del 5 por ciento de los quistes únicos no parasitarios del hígado. Nuestro objetivo es reportar un caso clínico y discutir algunos aspecto respecto al diagnóstico y tratamiento de este tipo de lesiones.

Recurrent Hepatic Alveolar Echinococcosis: Report of The First Case in Korea with Unproven Infection Route

Human alveolar echinococcosis (AE), a hepatic disorder that resembles liver cancer, is a highly aggressive and lethal zoonotic infection caused by the larval stage of the fox tapeworm, Echinococcus multilocularis. E. multilocularis is widely distributed in the northern hemisphere; the disease-endemic area stretches from north America through Europe to central and east Asia, including northern parts of Japan, but it has not been reported in Korea. Herein, we represent a first case of AE in Korea. A 41-year-old woman was found to have a large liver mass on routine medical examination. The excised mass showed multinodular, necrotic, and spongiform appearance with small irregular pseudocystic spaces. Microscopically, the mass was composed of chronic granulomatous inflammation with extensive coagulation necrosis and parasite-like structure, which was revealed as parasitic vesicles and laminated layer delineated by periodic acid-Schiff (PAS) stain. Clinical and histologic features were consistent with AE. After 8 years, a new liver mass and multiple metastatic pulmonary nodules were found and the recurred mass showed similar histologic features to the initial mass. She had never visited endemic areas of AE, and thus the exact infection route is unclear.